|
KMID : 1123920080220051196
|
|
Korean Journal of Oriental Physiology and Pathology
2008 Volume.22 No. 5 p.1196 ~ p.1201
|
|
|
Inhibitory Effect of Sorbus cortex Extract on (1,3)-β-Glucan Synthase
|
|
You Myung-Ja
Kim Bo-Mi
Lee Jeong-Ho
Lee Young-Haeng
Choi Kyu-Yoon
Baek Seung-Hwa
|
|
|
Abstract
|
|
|
|
A examination of the kinetic properties of UDP-glucose : (1,3)--glucan (callose) synthase from mung bean seedings (Sorbus cortex) shows that these enzymes have a complex interaction with UDP-glucose and various effectors. Deoxynojirimycin increased the inhibitory effect of (1,3)--glucan synthase at the concentration-dependent manner by fluorescence assay. The inhibitory effect of Fr. 2-16 (97.15%) showed higher than that of deoxynojirimycin (80.63%). Fr. 2-3 inhibited the growth of the Candida albicans at 1 mm inhibition zone by disk diffusion method. These results suggest that Sorbus cortex extract can be used as a stable antifungal material.
|
|
|
KEYWORD
|
|
|
Kinetic properties, (1, 3)-β-glucan (callose) synthase, Sorbus cortex, fluorescence assay, inhibitory effect, Candida albicans
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|